Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free NP Alfasigma USA, Inc. does not represent these product codes to be National Drug Codes (NDC). Product codes are formatted according to standard industry practice, to meet the formatting requirements of pharmacy and health insurance computer systems. CAS# 151533-22-1 CerefolinNAC bottle of 90 Product Code # 00525-0555-90. Description CerefolinNAC is a prescription medical food for use only under the supervision of a physician for the clinical dietary management of mild cognitive impairment and is specially formulated to meet the distinctive nutritional requirements for this condition. Each CerefolinNAC caplet is an oval coated beige colored caplet. Debossed with “PAL” on one side and “600” on the other. This product is not an orange book product. Storage Store at controlled room temperature 15(0)C to 30(0)C (59(0)F to 86(0)F) (See USP). Protect from heat, light and moisture. Recommended use The usual adult dose is one caplet daily or as directed under medical supervision.
Allergic reactions have been reported following the use of oral L-methylfolate Calcium. Mild transient diarrhea, itching, transitory exanthema and the feeling of swelling of the entire body has been associated with methylcobalamin. Nausea, vomiting, diarrhea, transient skin rash, flushing, epigastric pain, and constipation have been associated with N-acetyl-L-cysteine. Contains milk and soy Indications and usage CerefolinNAC is indicated for the distinct nutritional requirements of individuals with mild to moderate cognitive impairment who present with an increased risk for neurovascular oxidative stress and/or hyperhomocysteinemia; and/or suboptimal L-methylfolate and/or vitamin B12 levels in the cerebrospinal fluid, plasma, and/or red blood cells. CerefolinNAC caplets do not contain lactose, yeast or gluten.
CerefolinNAC is a prescription medical food for use only under the supervision of a physician. Contraindications CerefolinNAC is contraindicated in patients with known hypersensitivity to any of the components contained in this product. Headaches may be intensified in those taking N-acetyl-L-cysteine and nitrates for the treatment of angina.24 While the incidence of renal stones is low, those that do form renal stones, particularly cysteine stones should avoid CerefolinNAC. Do not administer CerefolinNAC to critically ill patients. N-acetyl-L-cysteine and its sulfhydryl metabolites could produce a false-positive result in the nitroprusside test for ketone bodies used in diabetes.24 N-acetyl-L-cysteine should be used with caution in those with a history of peptic ulcer disease since N-acetyl-L-cysteine may disrupt the gastric mucosal barrier. Medical foods are intended for a patient who has a limited or impaired capacity to ingest, digest, absorb, or metabolize ordinary foodstuffs or certain nutrients, or who has other special medically determined nutrient requirements, the dietary management of which cannot be achieved by the modification of the normal diet alone. Precautions General Folic acid, when administered in daily doses above 0.1mg, may obscure the detection of B12 deficiency (specifically, the administration of folic acid may reverse the hematological manifestations of B12 deficiency, including pernicious anemia, while not addressing the neurological manifestations). L-methylfolate Calcium may be less likely than folic acid to mask vitamin B12 deficiency. Folate therapy alone is inadequate for the treatment of a B12 deficiency. Use under medical supervision. Adverse reactions Allergic reactions have been reported following the use of oral L-methylfolate Calcium. Mild transient diarrhea, itching, transitory exanthema and the feeling of swelling of the entire body has been associated with methylcobalamin. Nausea, vomiting, diarrhea, transient skin rash, flushing, epigastric pain, and constipation have been associated with N-acetyl-L-cysteine. Contains milk and soy N-acetyl-L-cysteine clearance is reduced in those with chronic liver disease as well as in pre-term newborns. N-acetyl-L-cysteine should be avoided by nursing mothers.