SAMe 400

Dairy Free Women (not pregnant or lactating) Gluten Free Adult (18 - 50 Years) Vegan Vegetarian NP Dietary Supplement Jarrow Formulas SAMe 400 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken. Store in a cool, dry place. V Vegan For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon. Usage: Take 1 tablet per day on an empty stomach or as directed by your qualified healthcare professional.

Full potency 400 mg SAMe (net yield) is derived from 800 mg of SAMe tosylate disulfate. Jarrow Formulas SAMe 400 provides a full 400 mg SAMe (net yield) from 800 mg of SAMe tosylate disulfate. SAMe 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. Contains more of the active S,S form Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAMe is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAMe, the highest active level available. S-Adenosyl Methionine 400 mg (net yield) SAMe from 800 mg SAMe tosylate disulfate Highest concentration of Active S,S Form No wheat, gluten, soybeans, dairy, egg, fish/shellfish, or peanuts/tree nuts. EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption. Full potency pH-sensitive - food grade enteroguard coating Promotes: Joint strength Liver detoxification Mood and brain function Enteric-coated tablets SAMe has been clinically shown to have the following benefits: Joint Strength SAMe supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate. Brain Metabolism SAMe methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin). Liver SAMe metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase, glutathione reductase and glutathione-S-transferase), which are components of the body’s endogenous antioxidant network and important for liver function, including phase II detoxification. Suitable for vegetarians/vegans.

Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAMe. Keep out of the reach of children. Do not use if pregnant or nursing. Warning: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product.